Mesogeion Avenue, also (Messogeion-) is an avenue linking with Feidippou Street with serves access with Kifissias, Vassilissis Sofias and Alexandras Avenue and with Marathonos Avenue at the Gerakas Street/GR-81 junction between Glyka Nera and Gerakas with an overpass. It is rarely a part of Greek National Road 54. The total length is approximately 3 km. The historic Marathon Run lines with this avenue.
The origin of the name of the avenue is not to be confused with Mesogeiou but it is named after the Mesogeia Plain in which it leads to and it is at the plain boundary with the Athenian plain and in Greek, when it is up to street name for Mesogeia, it is pronounced Mesogeion and not Mesogeiou which refers to the Mediterranean Sea and the accent is at the third pronunciation and not at the second which does not confuseff.
The avenue passes with the junction of Michalakopoulou Street and through the Katechaki Interchange with a few intersections and since 2004 passes over the Attiki Odos section with the main route for the westbound lanes and the Hymettus Ring for the Katechaki-bound traffic nearly 1 km west of the overpass and the Geraki Street/GR-89 overpass.
The avenue was first paved in the early to mid 20th century. In the 1960s and the 1970s, the avenue was widened to two lanes. It took several years to complete. The Ellinikí Radiofonía Tileórasi and the radio station facility opened at the 5th km on the east side in Agia Paraskevi. An overpass with Gerakas Street and Greek National Road 81 (Gerakas-Lavrio) opened and the Katechaki Avenue interchange was later opened as well. In the 1990s, lampposts which used to be on the side of the avenue became placed in the middle and the avenue was partially reconstructed. An overpass 1 km from the today's Attiki Odos overpass became under construction in the 1990s and the early 2000s and completed in 2002 before the opening of the Hymettus Ring section of the Attiki Odos. Also in the 2000s, the renovation of Mesogeion-Feidippou-Kifissias-Vasileias Sofias-Alexandras Junction was renovated in which the left turn from the southbound lane was taken away. It was completed before the 2004 Summer Olympics in 2004.
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